Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing

BackgroundEffective skin repair requires rapid wound closure accompanied by precise extracellular matrix (ECM) remodeling and balanced cellular metabolism. Saliva-derived exosomes (S-Exo) have emerged as promising therapeutic agents due to their rich bioactive components; however, their mechanisms i...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Sijia Song, Rong Xiang, Siyu Chen, Jianbo Wu, Wenxia Chen, Xianyu Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	saliva-derived exosomes glycolysis metabolic reprogramming wound healing extracellular matrix remodeling fibroblasts
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1606716/full