GliaTrap is a biodegradable, non-swelling and non-inflammatory hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells

Abstract A significant factor in relapse and dismal prognosis of glioblastoma is the migrating glioblastoma cells, which diffuse away from the tumor mass into the brain parenchyma. Post-resection application of biomaterials to deliver cytotoxic agents against the invading glioblastoma cells has rece...

詳細記述

書誌詳細
出版年:Scientific Reports
主要な著者: Yusuke Suita, Saradha Miriyala, Deniz Merih-Toruner, Mattia Pizzagalli, Owen P. Leary, Weizhou Yue, Lingxiao Xie, Blessing Akobundu, Nathan Pertsch, Andras Fiser, Eduardo Fajardo, Jie Shen, Nikos Tapinos
フォーマット: 論文
言語:英語
出版事項: Nature Portfolio 2025-05-01
オンライン・アクセス:https://doi.org/10.1038/s41598-025-02977-x