The Novel Monoacylglycerol Lipase Inhibitor MJN110 Suppresses Neuroinflammation, Normalizes Synaptic Composition and Improves Behavioral Performance in the Repetitive Traumatic Brain Injury Mouse Model

Modulation of the endocannabinoid system has emerged as an effective approach for the treatment of many neurodegenerative and neuropsychological diseases. However, the underlying mechanisms are still uncertain. Using a repetitive mild traumatic brain injury (mTBI) mouse model, we found that there wa...

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發表在:	Cells
Main Authors:	Prabhuanand Selvaraj, Mikiei Tanaka, Jie Wen, Yumin Zhang
格式:	Article
語言:	英语
出版:	MDPI AG 2021-12-01
主題:	monoacylglycerol lipase inhibitor 2-arachidonyl glycerol glutamate receptors GABA receptors microglia neuronal cell death
在線閱讀:	https://www.mdpi.com/2073-4409/10/12/3454