Postoperative adjuvant chemotherapy in patients with stage II early onset colorectal cancer: exploration and discovery using real-world data and the SEER database

Background and aimThe incidence of early-onset colorectal cancer (EOCRC) is rising, yet intensive postoperative adjuvant chemotherapy (ACT) often results in overtreatment with minimal prognostic benefit. This study aims to assess the therapeutic necessity of ACT in stage II EOCRC patients and to ide...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Shikun Cao, Yihuan Qiao, Lijun Wu, Qi Chen, Kai Tian, Jipeng Li, Chungen Xing
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	early onset colorectal cancer adjuvant chemotherapy deficient mismatch repair survival landmark analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1566569/full