Sex-related differences in serum biomarker levels predict the activity and efficacy of immune checkpoint inhibitors in advanced melanoma and non-small cell lung cancer patients

Abstract Background Immune Checkpoint Inhibitors (ICIs) lead to durable response and a significant increase in long-term survival in patients with advanced malignant melanoma (MM) and Non-Small Cell Lung Cancer (NSCLC). The identification of serum cytokines that can predict their activity and effica...

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Bibliographic Details

Published in:	Journal of Translational Medicine
Main Authors:	Giulia Pasello, Aline S. C. Fabricio, Paola Del Bianco, Valentina Salizzato, Adolfo Favaretto, Luisa Piccin, Fable Zustovich, Alessio Fabozzi, Costanza De Rossi, Jacopo Pigozzo, Mattia De Nuzzo, Elia Cappelletto, Laura Bonanno, Dario Palleschi, Gian Luca De Salvo, Valentina Guarneri, Massimo Gion, Vanna Chiarion-Sileni
Format:	Article
Language:	English
Published:	BMC 2024-03-01
Subjects:	ICIs Predictive biomarkers Cytokines Melanoma NSCLC Precision medicine
Online Access:	https://doi.org/10.1186/s12967-024-04920-6