Potential of PINK1 and PARKIN Proteins as Biomarkers for Active Multiple Sclerosis: A Japanese Cohort Study

BackgroundMitochondrial dysfunction has been suggested to play an important role in all stages of multiple sclerosis (MS).ObjectiveTo determine the expression of two mitophagy-related proteins, PTEN-induced kinase 1 (PINK1) and PARKIN, in a cohort of Japanese patients with different neuroinflammator...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Davide Cossu, Kazumasa Yokoyama, Leonardo Antonio Sechi, Nobutaka Hattori
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Subjects:	mitophagy multiple sclerosis neuromyelitis optica spectrum disorders myelin oligodendrocytes glycoprotein (MOG) antibody disorders PINK1 PARKIN
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.681386/full