Sensitivity and specificity of a real-time reverse transcriptase polymerase chain reaction detecting feline coronavirus mutations in effusion and serum/plasma of cats to diagnose feline infectious peritonitis

Abstract Background Feline coronavirus (FCoV) exists as two pathotypes, and FCoV spike gene mutations are considered responsible for the pathotypic switch in feline infectious peritonitis (FIP) pathogenesis. The aim of this study was to evaluate sensitivity and specificity of a real-time reverse tra...

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Bibliographic Details

Published in:	BMC Veterinary Research
Main Authors:	Sandra Felten, Christian M. Leutenegger, Hans-Joerg Balzer, Nikola Pantchev, Kaspar Matiasek, Gerhard Wess, Herman Egberink, Katrin Hartmann
Format:	Article
Language:	English
Published:	BMC 2017-08-01
Subjects:	Feline infectious peritonitis (FIP) Reverse transcriptase polymerase chain reaction (RT-PCR) Feline coronavirus (FCoV) Feline enteric coronavirus (FECV) Feline infectious peritonitis virus (FIPV)
Online Access:	http://link.springer.com/article/10.1186/s12917-017-1147-8