Interferon-γ inhibits group B Streptococcus survival within human endothelial cells

Endothelial dysfunction is a major component of the pathophysiology of septicaemic group B Streptococcus (GBS) infections. Although cytokines have been shown to activate human umbilical vein endothelial cells (HUVECs), the capacity of interferon (IFN)-γ to enhance the microbicidal activity of HUVECs...

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Bibliographic Details

Published in:	Memorias do Instituto Oswaldo Cruz
Main Authors:	Viviane de Oliveira Freitas Lione, Michelle Hanthequeste Bittencourt dos Santos, Jessica Silva Santos de Oliveira, Ana Luiza Mattos-Guaraldi, Prescilla Emy Nagao
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2014-11-01
Subjects:	group B Streptococcus IFN-γ survival
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000700940&lng=en&tlng=en