Enrichment of Double RUNX1 Mutations in Acute Leukemias of Ambiguous Lineage

Acute leukemia of ambiguous lineage (ALAL) is a rare type of leukemia and represents an unmet clinical need. In fact, due to heterogeneity, substantial rarity and absence of clinical trials, there are no therapeutic guidelines available. We investigated the genetic basis of 10 cases of ALAL diagnose...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Gabriele Merati, Marianna Rossi, Anna Gallì, Elisa Roncoroni, Silvia Zibellini, Ettore Rizzo, Daniela Pietra, Cristina Picone, Barbara Rocca, Claudia Patricia Tobar Cabrera, Eleonora Gelli, Eugenio Santacroce, Luca Arcaini, Patrizia Zappasodi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Subjects:	Runx1 acute undifferentiated leukaemia myeloid genes acute leukemia of ambiguous lineage double mutations
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2021.726637/full