Neural signatures of indirect pathway activity during subthalamic stimulation in Parkinson’s disease

Abstract Deep brain stimulation (DBS) of the subthalamic nucleus (STN) produces an electrophysiological signature called evoked resonant neural activity (ERNA); a high-frequency oscillation that has been linked to treatment efficacy. However, the single-neuron and synaptic bases of ERNA are unsubsta...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Leon A. Steiner, David Crompton, Srdjan Sumarac, Artur Vetkas, Jürgen Germann, Maximilian Scherer, Maria Justich, Alexandre Boutet, Milos R. Popovic, Mojgan Hodaie, Suneil K. Kalia, Alfonso Fasano, William D. Hutchison WD, Andres M. Lozano, Milad Lankarany, Andrea A. Kühn, Luka Milosevic
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Online Access:https://doi.org/10.1038/s41467-024-47552-6