Differential Effects of D-Galactose Supplementation on Golgi Glycosylation Defects in TMEM165 Deficiency

Glycosylation is a ubiquitous and universal cellular process in all domains of life. In eukaryotes, many glycosylation pathways occur simultaneously onto proteins and lipids for generating a complex diversity of glycan structures. In humans, severe genetic diseases called Congenital Disorders of Gly...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Zoé Durin, Marine Houdou, Willy Morelle, Lydia Barré, Aurore Layotte, Dominique Legrand, Mohamed Ouzzine, François Foulquier
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Subjects:	CDG TMEM165-CDG glycosylation galactose manganese
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.903953/full