A truncated anti-CRISPR protein prevents spacer acquisition but not interference

Phages can use ACR proteins that inhibit the adaptive immunity activities of bacterial CRISPR-Cas systems. Here, Philippe et al. show that these systems can block ACR-containing phages by targeting the acr gene, and this can select for phage mutants carrying a deletion within acr that does not block...

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發表在:	Nature Communications
Main Authors:	Cécile Philippe, Carlee Morency, Pier-Luc Plante, Edwige Zufferey, Rodrigo Achigar, Denise M. Tremblay, Geneviève M. Rousseau, Adeline Goulet, Sylvain Moineau
格式:	Article
語言:	英语
出版:	Nature Portfolio 2022-05-01
在線閱讀:	https://doi.org/10.1038/s41467-022-30310-x