Effect of herb-drug interactions of Bacopa monnieri Linn. (Brahmi) formulation on the pharmacokinetics of amitriptyline in rats

ABSTRACT Interactions between herbs and drugs may increase or decrease the pharmacological or toxicological effects of either component. Experimental data on the pharmacokinetic interactions between herbal products and drugs are limited. This study attempted to investigate the effect of Bacopa monni...

Full description

Bibliographic Details

Published in:	Brazilian Journal of Pharmaceutical Sciences
Main Authors:	Fowad Khurshid, Jeyabalan Govindasamy, Habibullah Khalilullah, Mohammed Shivli Nomani, Mudassar Shahid, Md Ruhal Ain, Mohammad Sultan Alsultan
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2018-03-01
Subjects:	Herbal drug interaction Bacopa monnieri/effects Amitriptyline/pharmacokinetics CYP450 Bioavailability.
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400610&lng=en&tlng=en