Comprehensive Analysis of the Genetic Variation in the <i>LPA</i> Gene from Short-Read Sequencing

Lipoprotein (a) (Lp(a)) is a risk factor for cardiovascular diseases and mainly regulated by the complex <i>LPA</i> gene. We investigated the types of variation in the <i>LPA</i> gene and their predictive performance on Lp(a) concentration. We determined the Kringle IV-type 2...

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Bibliographic Details
Published in:BioMed
Main Authors: Raphael O. Betschart, Georgios Koliopanos, Paras Garg, Linlin Guo, Massimiliano Rossi, Sebastian Schönherr, Stefan Blankenberg, Raphael Twerenbold, Tanja Zeller, Andreas Ziegler
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Subjects:
genome-wide association study
lipoprotein(a)
Kringle IV-2 repeat
KIV-2
short tandem repeat
whole genome sequencing
Online Access:https://www.mdpi.com/2673-8430/4/2/13

Internet

https://www.mdpi.com/2673-8430/4/2/13

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