CTCF coordinates cell fate specification via orchestrating regulatory hubs with pioneer transcription factors

Summary: CCCTC-binding factor (CTCF), a ubiquitously expressed architectural protein, has emerged as a key regulator of cell identity gene transcription. However, the precise molecular mechanism underlying specialized functions of CTCF remains elusive. Here, we investigate the mechanism through inte...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Yuting Liu, Xin Wan, Hu Li, Yingxi Chen, Xiaodi Hu, Hebing Chen, Dahai Zhu, Cheng Li, Yong Zhang
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Subjects:	CP: Stem cell research CP: Molecular biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723012718