Formulation optimization of furosemide floating-bioadhesive matrix tablets using waste-derived Citrus aurantifolia peel pectin as a polymer

Abstract Natural polymers such as pectin have garnered significant interest in recent years due to their potential applications in gastroretentive drug delivery systems. Gastroretentive dosage forms are intended to extend the emptying time of drugs in the gastrointestinal tract. Accordingly, this st...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Ebrahim Abdela Siraj, Yohannes Mulualem, Fantahun Molla, Ashagrachew Tewabe Yayehrad, Anteneh Belete
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Subjects:
Citrus aurantifolia
Floating
Bioadhesive
Pectin
Optimization
Furosemide
Online Access:https://doi.org/10.1038/s41598-025-95732-1

Internet

https://doi.org/10.1038/s41598-025-95732-1

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