The roles of METTL3 on autophagy and proliferation of vascular smooth muscle cells are mediated by mTOR rather than by CDK1

Abstract Background Aberrant proliferation of vascular smooth muscle cells (VSMCs) is the cause of neointima formation followed by vascular injury. Autophagy is involved in this pathological process, but its function is controversial. Recently, we found that methyltransferase like 3 (METTL3) inhibit...

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Bibliographic Details

Published in:	Cell Division
Main Authors:	Hanshen Luo, Xingliang Wu, Bo Huo, Liyuan Liu, Ding-Sheng Jiang, Xin Yi
Format:	Article
Language:	English
Published:	BMC 2023-08-01
Subjects:	Vascular smooth muscle cell Autophagy Proliferation METTL3 mTOR CDK1/CDC2
Online Access:	https://doi.org/10.1186/s13008-023-00096-5