Opioids and Vitamin C: Known Interactions and Potential for Redox-Signaling Crosstalk

Opioids are among the most widely used classes of pharmacologically active compounds both clinically and recreationally. Beyond their analgesic efficacy via μ opioid receptor (MOR) agonism, a prominent side effect is central respiratory depression, leading to systemic hypoxia and free radical genera...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Mackenzie Newman, Heather Connery, Jonathan Boyd
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Subjects:	vitamin C opioids mu opioid receptor oxidative stress signaling metabolism
Online Access:	https://www.mdpi.com/2076-3921/11/7/1267