Enasidenib‐induced hepatitis in an individual with Type II D2‐hydroxyglutaric aciduria

Abstract Type II D‐2‐Hydroxyglutaric aciduria (T2D2HGA) is caused by a gain‐of‐function pathogenic variant in Isocitrate Dehydrogenase 2 (IDH2). Patients with T2D2HGA commonly present with developmental delay, seizures, cardiomyopathy, and arrhythmias. The recently approved IDH2‐inhibitor Enasidenib...

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Bibliographic Details
Published in:JIMD Reports
Main Authors: Jessica I. Gold, Arianna K. Stefanatos, Jamie L. Fraser, Adeline Vanderver, Sanmati Cuddapah
Format: Article
Language:English
Published: Wiley 2024-05-01
Subjects:
IDH2 inhibitor
novel treatment
organic acidurias
Type II D2‐hydroxyglutaric aciduria
Online Access:https://doi.org/10.1002/jmd2.12421

Internet

https://doi.org/10.1002/jmd2.12421

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