mRNP granule proteins Fmrp and Dcp1a differentially regulate mRNP complexes to contribute to control of muscle stem cell quiescence and activation

Abstract Background During skeletal muscle regeneration, satellite stem cells use distinct pathways to repair damaged myofibers or to self-renew by returning to quiescence. Cellular/mitotic quiescence employs mechanisms that promote a poised or primed state, including altered RNA turnover and transl...

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Bibliographic Details

Published in:	Skeletal Muscle
Main Authors:	Nainita Roy, Swetha Sundar, Malini Pillai, Farah Patell-Socha, Sravya Ganesh, Ajoy Aloysius, Mohammed Rumman, Hardik Gala, Simon M. Hughes, Peter S. Zammit, Jyotsna Dhawan
Format:	Article
Language:	English
Published:	BMC 2021-07-01
Subjects:	Quiescence mRNP granule Translational control mRNA decay Skeletal muscle Myoblast
Online Access:	https://doi.org/10.1186/s13395-021-00270-9