Case Report: Immune Checkpoint Blockade Plus Interferon-Γ Add-On Antifungal Therapy in the Treatment of Refractory Covid-Associated Pulmonary Aspergillosis and Cerebral Mucormycosis

Invasive fungal diseases (IFD) still cause substantial morbidity and mortality, and new therapeutic approaches are urgently needed. Recent data suggest a benefit of checkpoint inhibitors (ICI). We report the case of a diabetic patient with refractory IFD following a SARSCoV-2 infection treated by IC...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Alexandra Serris, Amani Ouedrani, Fabrice Uhel, Marianne Gazzano, Vincent Bedarida, Claire Rouzaud, Marie-Elisabeth Bougnoux, Jean-Herlé Raphalen, Sylvain Poirée, Olivier Lambotte, Guillaume Martin-Blondel, Fanny Lanternier
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Subjects:	invasive fungal disease anti-PD 1 cerebral mucormycosis covid-associated pulmonary aspergillosis immunotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.900522/full