Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from <i>Conus ateralbus</i>

The venom of cone snails has been proven to be a rich source of bioactive peptides that target a variety of ion channels and receptors. α-Conotoxins (αCtx) interact with nicotinic acetylcholine receptors (nAChRs) and are powerful tools for investigating the structure and function of the various nACh...

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Bibliographic Details

Published in:	Marine Drugs
Main Authors:	Jorge L. B. Neves, Cristoval Urcino, Kevin Chase, Cheryl Dowell, Arik J. Hone, David Morgenstern, Victor M. Chua, Iris Bea L. Ramiro, Julita S. Imperial, Lee S. Leavitt, Jasmine Phan, Fernando A. Fisher, Maren Watkins, Shrinivasan Raghuraman, Jortan O. Tun, Beatrix M. Ueberheide, J. Michael McIntosh, Vitor Vasconcelos, Baldomero M. Olivera, Joanna Gajewiak
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Subjects:	conotoxin nAChRs Constellation Pharmacology DRG neurons
Online Access:	https://www.mdpi.com/1660-3397/22/3/118