Mammalian Display Platform for the Maturation of Bispecific TCR-Based Molecules

Bispecific T cell receptor (TCR)-based molecules capable of redirecting and activating T cells towards tumor cells represent a novel and promising class of biotherapeutics for the treatment of cancer. Usage of TCRs allows for targeting of intracellularly expressed and highly selective cancer antigen...

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Bibliographic Details

Published in:	Antibodies
Main Authors:	Janine Dilchert, Martin Hofmann, Felix Unverdorben, Roland Kontermann, Sebastian Bunk
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Subjects:	mammalian display CHO RMCE TCR bispecific maturation
Online Access:	https://www.mdpi.com/2073-4468/11/2/34