Clonal hematopoiesis is associated with reduced response to atezolizumab in non-small cell lung cancer

Background The acquisition of somatic mutations associated with the expansion of certain hematopoietic stem cells is known as clonal hematopoiesis (CH). Despite evidence of CH association with age-related pro-inflammatory diseases, little is known about its role in the response to antitumor immune m...

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Bibliographic Details
Published in:Journal for ImmunoTherapy of Cancer
Main Authors: Ira Mellman, Minu Srivastava, Mark I McCarthy, Kipper Fletez-Brant, Christian Hammer, Barzin Nabet, Vylyny Chat
Format: Article
Language:English
Published: BMJ Publishing Group 2025-09-01
Online Access:https://jitc.bmj.com/content/13/9/e011565.full