Erythromycin Restores Osteoblast Differentiation and Osteogenesis Suppressed by <i>Porphyromonas gingivalis</i> Lipopolysaccharide

The macrolide erythromycin (ERM) inhibits excessive neutrophil accumulation and bone resorption in inflammatory tissues. We previously reported that the expression of developmental endothelial locus-1 (DEL-1), an endogenous anti-inflammatory factor induced by ERM, is involved in ERM action. Furtherm...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Hikaru Tamura, Tomoki Maekawa, Hisanori Domon, Kridtapat Sirisereephap, Toshihito Isono, Satoru Hirayama, Takumi Hiyoshi, Karin Sasagawa, Fumio Takizawa, Takeyasu Maeda, Yutaka Terao, Koichi Tabeta
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	macrolides periodontitis <i>Porphyromonas gingivalis</i> lipopolysaccharide osteoblastogenesis developmental endothelial locus-1
Online Access:	https://www.mdpi.com/1424-8247/16/2/303