Backward simulation for inferring hidden biomolecular kinetic profiles

Summary: Our backward simulation (BS) is an approach to infer the dynamics of individual components in ordinary differential equation (ODE) models, given the information on relatively downstream components or their sums. Here, we demonstrate the use of BS to infer protein synthesis rates with a give...

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Bibliographic Details
Published in:STAR Protocols
Main Authors: Junghun Chae, Roktaek Lim, Cheol-Min Ghim, Pan-Jun Kim
Format: Article
Language:English
Published: Elsevier 2021-12-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672100664X