Environmental enrichment alters protein expression as well as the proteomic response to cocaine in rat nucleus accumbens

Prior research demonstrated that environmental enrichment creates individual differences in behavior leading to a protective addiction phenotype in rats. Understanding the mechanisms underlying this phenotype will guide selection of targets for much-needed novel pharmacotherapeutics. The current stu...

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Bibliographic Details

Published in:	Frontiers in Behavioral Neuroscience
Main Authors:	Cheryl F. Lichti, Xiuzhen eFan, Robert D. English, Yafang eZhang, Dingge eLi, Fanping eKong, Mala eSinha, Clark R. Andersen, Heidi eSpratt, Bruce A. Luxon, Thomas A. Green
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-07-01
Subjects:	Cocaine Proteomics drug addiction Drug abuse Differential rearing label-free quantification
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00246/full