Resolution of a Metastable Racemic Compound of Anhydrous Phencyphos by Hydrate Formation

The resolution of 2-hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide (phencyphos) was achieved by dissolution of anhydrous racemic phencyphos, a racemic compound, accompanied by simultaneous secondary nucleation of the dissolved racemate on to enantiopure seeds of phencyphos hydrate, a...

Full description

Bibliographic Details

Published in:	Crystals
Main Authors:	Michel Leeman, Richard M. Kellogg
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	resolution phencyphos pseudo-polymorph conglomerate racemic compound
Online Access:	https://www.mdpi.com/2073-4352/11/10/1225