Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase

Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) infection has caused huge economic losses in global swine industry over the last 37 years. PRRSV commercial vaccines are not effective against all epidemic PRRSV strains. In this study we performed a high-throughput screening (HTS)...

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Bibliographic Details
Published in:Veterinary Research
Main Authors: Yuanqi Yang, Yanni Gao, Lujie Zhang, Xing Liu, Yangyang Sun, Juan Bai, Ping Jiang
Format: Article
Language:English
Published: BMC 2023-12-01
Subjects:
Vidofludimus
PRRSV infection
antiviral
dihydroorotate dehydrogenase
broad-spectrum
Online Access:https://doi.org/10.1186/s13567-023-01251-0

Internet

https://doi.org/10.1186/s13567-023-01251-0

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