Phenotypic heterogeneity unveils a negative correlation between antibiotic resistance and quorum sensing in Pseudomonas aeruginosa clinical isolates

Colonization of Pseudomonas aeruginosa in the lung environments frequently leads to the enrichment of strains displaying enhanced antibiotic resistance and reduced production of quorum-sensing (QS) controlled products. However, the relationship between the emergence of QS deficient variants and anti...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Xiting Yang, Qianglin Zeng, Shiyi Gou, Yi Wu, Xiaoling Ma, Hang Zou, Kelei Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Subjects:	Pseudomonas aeruginosa COPD quorum-sensing antibiotic resistance mutation evolution
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2024.1327675/full