Computational modeling of frequency-dependent neocortical response to thalamic neurostimulation in epilepsy.

The therapeutic application of centromedian nucleus stimulation (CMS) has been limited by uncertainties regarding its mechanism of action. In this study, we used stereoelectro-encephalography (SEEG) signals recorded from a patient with refractory epilepsy, caused by focal cortical dysplasia, which i...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Linda Iris Joseph Tomy, Elif Köksal-Ersöz, Anca Nica, Maxime Yochum, Pascal Benquet, Fabrice Wendling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Online Access:https://doi.org/10.1371/journal.pcbi.1012943