NSD1 in erythroid differentiation and leukemogenesis

We have uncovered a novel role for the nuclear receptor-binding SET domain protein 1 (NSD1) in human and murine erythroid differentiation. Mechanistically, we found that the histone methyltransferase activity of NSD1 is essential for chromatin binding, protein interactions and target gene activation...

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Bibliographic Details
Published in:Molecular & Cellular Oncology
Main Authors: Samantha Tauchmann, Marwa Almosailleakh, Juerg Schwaller
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Subjects:
histone methyltransferase
erythroleukemia
erythroid differentiation
nsd1
gata1
Online Access:http://dx.doi.org/10.1080/23723556.2020.1809919

Internet

http://dx.doi.org/10.1080/23723556.2020.1809919

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