Metformin: update on mechanisms of action on liver diseases

Substantial attention has been paid to the various effects of metformin on liver diseases; the liver is the targeted organ where metformin exerts its antihyperglycemic properties. In non-alcoholic fatty liver disease (NAFLD), studies have shown that metformin affects the ATP/AMP ratio to activate AM...

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Bibliographic Details

Published in:	Frontiers in Nutrition
Main Authors:	Gaoyi Ruan, Fangquan Wu, Dibang Shi, Hongxia Sun, Fangyan Wang, Changlong Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Subjects:	non-alcoholic liver disease metformin cirrhosis AMPK pathway drug-induced liver injury
Online Access:	https://www.frontiersin.org/articles/10.3389/fnut.2023.1327814/full