In vitro evidence of HER2-selective cytotoxicity by scFv(Herceptin)-PE-STXA immunotoxin in gastric cancer cells

The delivery of therapeutic agents in a targeted manner shows great potential for improving the degree of efficacy in cancer therapies by minimizing harm for normal tissues and reducing treatment-related complications. Among patients with gastric cancer, the HER2 receptor is expressed in approximate...

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Bibliographic Details

Published in:	Biochemistry and Biophysics Reports
Main Authors:	Hamid Sedighian, Arash Abdi, Zoleikha Goleij, Mahdi Fasihi-Ramandi, Abbas Ali Imani Fooladi
Format:	Article
Language:	English
Published:	Elsevier 2025-09-01
Subjects:	HER2 Gastric cancer Apoptosis Herceptin Targeted cancer immunotherapy
Online Access:	http://www.sciencedirect.com/science/article/pii/S240558082500305X