Optimization of PLGA Nanoparticle Formulation via Microfluidic and Batch Nanoprecipitation Techniques

Polymeric nanoparticles based on poly(lactic-co-glycolic acid) (PLGA) are widely used in drug delivery, yet scalable and reproducible production methods remain a major challenge. In this study, we combine experimental nanoprecipitation and computational fluid dynamics (CFD) modeling to optimize PLGA...

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Bibliographic Details
Published in:Micromachines
Main Authors: Gül Kozalak, Salar Heyat Davoudian, Evangelos Natsaridis, Nubia Gogniat, Ali Koşar, Oya Tagit
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Subjects:
PLGA nanoparticles
nanoprecipitation
design of experiments
microfluidics
computational fluid dynamics
Online Access:https://www.mdpi.com/2072-666X/16/9/972

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https://www.mdpi.com/2072-666X/16/9/972

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