PD-1/PD-L1 immune checkpoint blockade in breast cancer: research insights and sensitization strategies

Abstract Immunotherapy targeting programmed cell death-1 (PD-1) and PD-L1 immune checkpoints has reshaped treatment paradigms across several cancers, including breast cancer. Combining PD-1/PD-L1 immune checkpoint blockade (ICB) with chemotherapy has shown promising efficacy in both early and metast...

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Bibliographic Details

Published in:	Molecular Cancer
Main Authors:	Menglei Jin, Jun Fang, Junwen Peng, Xintian Wang, Ping Xing, Kunpeng Jia, Jianming Hu, Danting Wang, Yuxin Ding, Xinyu Wang, Wenlu Li, Zhigang Chen
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Subjects:	Breast cancer PD-1/PD-L1 Immune checkpoint blockade Clinical trials Biomarkers Sensitization strategies
Online Access:	https://doi.org/10.1186/s12943-024-02176-8