Green ultrasound‑assisted deep eutectic solvent extraction of flavonoid enzyme inhibitors from Blumea aromatica: process optimization, characterization, and mechanistic insights into α‑glucosidase and tyrosinase inhibition

A green ultrasound-assisted deep eutectic solvent (UAE–DES) method was optimised for extracting flavonoid enzyme inhibitors from Blumea aromatica. Optimal conditions (choline chloride-1,4-butanediol 1:3 molar ratio, 43% water content, 50 mL/g liquid-to-solid ratio, 80 °C ultrasound for 48 min) yield...

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Bibliographic Details

Published in:	Journal of Enzyme Inhibition and Medicinal Chemistry
Main Authors:	Wei Dai, Liping Dai, Tao Su, Qin Lin, Zhiwen Lin, Shuxin Ye, Peihao Xu, Hongfeng Chen, Xilong Zheng
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Blumea aromatica deep eutectic solvent flavonoid extraction α‑Glucosidase inhibition tyrosinase inhibition
Online Access:	https://www.tandfonline.com/doi/10.1080/14756366.2025.2552445