Spheroids derived from the stromal vascular fraction of adipose tissue self-organize in complex adipose organoids and secrete leptin

Abstract Background Adipose tissue-derived stromal vascular fraction (SVF) harbors multipotent cells with potential therapeutic relevance. We developed a method to form adipose spheroids (AS) from the SVF with complex organoid structure and enhanced leptin secretion upon insulin stimulation. Methods...

Full description

Bibliographic Details
Published in:Stem Cell Research & Therapy
Main Authors: Fermín Robledo, Lila González-Hodar, Pablo Tapia, Ana-María Figueroa, Fernando Ezquer, Víctor Cortés
Format: Article
Language:English
Published: BMC 2023-04-01
Subjects:
Organoid
Spheroid
Adipose tissue
Leptin
Adipogenesis
Online Access:https://doi.org/10.1186/s13287-023-03262-2

Internet

https://doi.org/10.1186/s13287-023-03262-2

Similar Items