Large-Scale Solvent-Free Chlorination of Hydroxy-Pyrimidines, -Pyridines, -Pyrazines and -Amides Using Equimolar POCl3

Chlorination with equimolar POCl3 can be efficiently achieved not only for hydroxypyrimidines, but also for many other substrates such as 2-hydroxy-pyridines, -quinoxalines, or even -amides. The procedure is solvent-free and involves heating in a sealed reactor at high temperatures using one equival...

詳細記述

書誌詳細

出版年:	Molecules
主要な著者:	Zhihua Sun, Yongjia Shen, Ye Xiang, Han Wang, Kun Wen, Le Wang, Xiaocheng Xu
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2012-04-01
主題:	solvent-free chlorination phosphorous oxychloride (POCl3)
オンライン･アクセス:	http://www.mdpi.com/1420-3049/17/4/4533/