Treg derived Amphiregulin protects from murine lupus nephritis via tissue reparative effects

Abstract Systemic lupus erythematosus (SLE) is a common autoimmune disease that affects multiple organ systems. Among the most severe manifestations of SLE is lupus nephritis (LN), which causes particularly high morbidity. Recently, we identified amphiregulin (AREG), an epidermal growth factor recep...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Laura-Isabell Ehnold, Simon Melderis, Julia Hagenstein, Matthias T. Warkotsch, Viona Laas, Frederic C. Feindt, Hui Wu, Tobias B. Huber, Florian Grahammer, Oliver M. Steinmetz
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-03-01
Online Access:	https://doi.org/10.1038/s41598-025-91636-2