Biocompatible PEO-b-PCL Nanosized Micelles as Drug Carriers: Structure and Drug–Polymer Interactions

We report on the preparation of drug nanocarriers by encapsulating losartan potassium (LSR) into amphiphilic block copolymer micelles, utilizing the biocompatible/biodegradable poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. The PEO-b-PCL micelles and LSR-loaded PEO-b-PCL...

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Bibliographic Details

Published in:	Nanomaterials
Main Authors:	Angeliki Chroni, Thomas Mavromoustakos, Stergios Pispas
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Subjects:	amphiphilic block copolymers polymeric nanocarriers drug delivery systems organic solvent evaporation method drug encapsulation drug–polymer intermolecular interactions
Online Access:	https://www.mdpi.com/2079-4991/10/9/1872