HTLV-1 biofilm polarization maintained by tetraspanin CD82 is required for efficient viral transmission

ABSTRACTThe human T-lymphotropic virus type 1 (HTLV-1) is an oncogenic retrovirus whose transmission relies primarily on cell-to-cell contacts as cell-free viruses are poorly infectious. Among the intercellular transmission routes described, HTLV-1 biofilms are adhesive structures polarized at the c...

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Bibliographic Details

Published in:	mBio
Main Authors:	Coline Arone, Samuel Martial, Julien Burlaud-Gaillard, Maria-Isabel Thoulouze, Philippe Roingeard, Hélène Dutartre, Delphine Muriaux
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-12-01
Subjects:	HTLV-1 Gag viral biofilms cell-to-cell viral transmission tetraspanins CD82
Online Access:	https://journals.asm.org/doi/10.1128/mbio.01326-23