Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy

Mesial temporal lobe epilepsy is the most common type of focal epilepsy, imposing a significant burden on the health care system worldwide. Approximately one-third of patients with this disease who do not adequately respond to pharmacotherapy are considered drug-resistant subjects. Despite having so...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Authors:	Elena A. Filimonova, Anton A. Pashkov, Galina I. Moysak, Anastasia Y. Tropynina, Svetlana Y. Zhanaeva, Anna A. Shvaikovskaya, Anna A. Akopyan, Konstantin V. Danilenko, Lyubomir I. Aftanas, Maria A. Tikhonova, Jamil A. Rzaev
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Subjects:	mesial temporal lobe epilepsy drug-resistant epilepsy BDNF MR morphometry FreeSurfer hippocampus
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2023.1217702/full