A hominoid-specific endogenous retrovirus may have rewired the gene regulatory network shared between primordial germ cells and naïve pluripotent cells.

Mammalian germ cells stem from primordial germ cells (PGCs). Although the gene regulatory network controlling the development of germ cells such as PGCs is critical for ensuring gamete integrity, substantial differences exist in this network among mammalian species, suggesting that this network has...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Jumpei Ito, Yasunari Seita, Shohei Kojima, Nicholas F Parrish, Kotaro Sasaki, Kei Sato
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-05-01
Online Access:	https://doi.org/10.1371/journal.pgen.1009846