Measurement of 8‐hydroxy‐2′‐deoxyguanosine in serum and cerebrospinal fluid of horses with neuroaxonal degeneration and other causes of proprioceptive ataxia

Abstract Background Eight‐hydroxy‐2′‐deoxyguanosine (8‐OHdG), a biomarker of oxidative damage evaluated in human neurodegenerative disease, has potential to correlate with postmortem diagnosis of neuroaxonal dystrophy/degenerative myeloencephalopathy (NAD/DM) in horses. Hypothesis We hypothesized th...

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Bibliographic Details

Published in:	Journal of Veterinary Internal Medicine
Main Authors:	Megan Palmisano, Jeaneen Kulp, Susan Bender, Darko Stefanovski, Mary Robinson, Amy Johnson
Format:	Article
Language:	English
Published:	Oxford University Press 2024-03-01
Subjects:	ataxia equine degenerative myeloencephalopathy (EDM) equine neuroaxonal dystrophy (eNAD) neurodegenerative oxidative damage
Online Access:	https://doi.org/10.1111/jvim.16988