Absolute Quantification of Endogenous Ras Isoform Abundance.

Ras proteins are important signalling hubs situated near the top of networks controlling cell proliferation, differentiation and survival. Three almost identical isoforms, HRAS, KRAS and NRAS, are ubiquitously expressed yet have differing biological and oncogenic properties. In order to help underst...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Craig J Mageean, John R Griffiths, Duncan L Smith, Michael J Clague, Ian A Prior
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Online Access:https://doi.org/10.1371/journal.pone.0142674