Characterization of iRGD-Ligand Modified Arginine-Histidine-Rich Peptides for Nucleic Acid Therapeutics Delivery to αvβ3 Integrin-Expressing Cancer Cells

Efficient and specific delivery of nucleic acid (NA) therapeutics to tumor cells is extremely important for cancer gene therapy. Various therapeutic strategies include delivery of DNA-therapeutics such as immunostimulatory or suicide genes and delivery of siRNA-therapeutics able to silence expressio...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Anna Egorova, Alexander Selutin, Marianna Maretina, Sergei Selkov, Vladislav Baranov, Anton Kiselev
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Subjects:	nonviral gene delivery siRNA delivery receptor targeting peptide-based carriers integrin iRGD
Online Access:	https://www.mdpi.com/1424-8247/13/10/300