T-Bet Deficiency Attenuates Bile Duct Injury in Experimental Biliary Atresia

Biliary atresia (BA) is an obstructive neonatal cholangiopathy leading to liver cirrhosis and end stage liver disease. A Kasai portoenterostomy may restore biliary drainage, but most patients ultimately require liver transplantation for survival. At diagnosis, immune cells within the liver of patien...

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Bibliographic Details

Published in:	Cells
Main Authors:	Sujit K. Mohanty, Bryan Donnelly, Haley Temple, Alexander Bondoc, Monica McNeal, Greg Tiao
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Subjects:	cholestasis bile duct STAT1 RRV T-bet
Online Access:	https://www.mdpi.com/2073-4409/10/12/3461