Satellite cell contribution to disease pathology in Duchenne muscular dystrophy

Progressive muscle weakness and degeneration characterize Duchenne muscular dystrophy (DMD), a lethal, x-linked neuromuscular disorder that affects 1 in 5,000 boys. Loss of dystrophin protein leads to recurrent muscle degeneration, progressive fibrosis, chronic inflammation, and dysfunction of skele...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Kasun Kodippili, Michael A. Rudnicki
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-05-01
Subjects:	Duchenne muscular dystrophy satellite cells skeletal muscle stem cells muscle regeneration myogenesis dystrophin
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2023.1180980/full