Bioengineered Human Stromal Lenticule for Recombinant Human Nerve Growth Factor Release: A Potential Biocompatible Ocular Drug Delivery System

Small incision lenticule extraction (SMILE), is a surgical procedure for the myopia correction, during which a corneal stromal lenticule is extracted. Given that we have previously demonstrated how this discarded tissue could be repurposed as a bio-scaffold for stromal engineering, this study aimed...

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Bibliographic Details

Published in:	Frontiers in Bioengineering and Biotechnology
Main Authors:	Leonardo Mastropasqua, Mario Nubile, Giuseppina Acerra, Nicola Detta, Letizia Pelusi, Manuela Lanzini, Simone Mattioli, Manuela Santalucia, Laura Pietrangelo, Marcello Allegretti, Harminder S. Dua, Jodhbir S. Mehta, Assunta Pandolfi, Domitilla Mandatori
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Subjects:	decellularization drug delivery microparticles nerve growth factor scaffold smile
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2022.887414/full